Evidence of an Antimicrobial-Immunomodulatory Role of Atlantic Salmon Cathelicidins during Infection with Yersinia ruckeri

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Evidence of an Antimicrobial-Immunomodulatory Role of Atlantic Salmon Cathelicidins during Infection with Yersinia ruckeri

Cathelicidins are a family of antimicrobial peptides that act as effector molecules of the innate immune system with broad-spectrum antimicrobial properties. These evolutionary conserved cationic host-defence peptides are integral components of the immune response of fish, which are generally believed to rely heavily on innate immune defences to invading pathogens. In this study we showed that ...

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Yersinia ruckeri Isolates Recovered from Diseased Atlantic Salmon (Salmo salar) in Scotland Are More Diverse than Those from Rainbow Trout (Oncorhynchus mykiss) and Represent Distinct Subpopulations.

UNLABELLED Yersinia ruckeri is the etiological agent of enteric redmouth (ERM) disease of farmed salmonids. Enteric redmouth disease is traditionally associated with rainbow trout (Oncorhynchus mykiss, Walbaum), but its incidence in Atlantic salmon (Salmo salar) is increasing. Yersinia ruckeri isolates recovered from diseased Atlantic salmon have been poorly characterized, and very little is kn...

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Chemical composition and in vitro antimicrobial activity of some Iranian medical herbs against Yersinia ruckeri

Increasing bacterial resistance to commercial antibiotics has led to considering medicinal herb applications. This study aimed to identify chemical composition of essential oil of some native medical herbs and their antibacterial activity against Yersinia ruckeri compared with Enrofloxacin in in vitro experiments. The antibacterial activities of ethanolic extracts and essential oils of Eryngium...

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Chemical composition and in vitro antimicrobial activity of some Iranian medical herbs against Yersinia ruckeri

Increasing bacterial resistance to commercial antibiotics has led to considering medicinal herb applications. This study aimed to identify chemical composition of essential oil of some native medical herbs and their antibacterial activity against Yersinia ruckeri compared with Enrofloxacin in in vitro experiments. The antibacterial activities of ethanolic extracts and essential oils of Eryngium...

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Immunomodulatory properties of defensins and cathelicidins.

Host defence peptides are a conserved component of the innate immune response in all complex life forms. In humans, the major classes of host defence peptides include the alpha- and beta-defensins and the cathelicidin, hCAP-18/LL-37. These peptides are expressed in the granules of neutrophils and by a wide variety of tissue types. They have many roles in the immune response including both indir...

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ژورنال

عنوان ژورنال: PLoS ONE

سال: 2011

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0023417